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Mutations causing aminotriazole resistance and temperature sensitivity reside in gyrB, which encodes the B subunit of DNA gyrase.

Certain mutations in gyrA and gyrB, the genes encoding the two subunits of DNA gyrase, are known to influence expression of the his operon (K. E. Rudd and R. Menzel, Proc. Natl. Acad. Sci. USA 84:517-521, 1987). Such mutations lead to a decrease in tRNA(His) levels and consequently to an attenuator-...

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Dettagli Bibliografici
Pubblicato in:J Bacteriol
Autori principali: Toone, W M, Rudd, K E, Friesen, J D
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1992
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC206392/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1322887/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.174.16.5479-5481.1992
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