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Drosophila melanogaster auxilin regulates the internalization of Delta to control activity of the Notch signaling pathway

We have isolated mutations in the Drosophila melanogaster homologue of auxilin, a J-domain–containing protein known to cooperate with Hsc70 in the disassembly of clathrin coats from clathrin-coated vesicles in vitro. Consistent with this biochemical role, animals with reduced auxilin function exhibi...

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Bibliografski detalji
Glavni autori: Hagedorn, Elliott J., Bayraktar, Jennifer L., Kandachar, Vasundhara R., Bai, Ting, Englert, Dane M., Chang, Henry C.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063844/
https://ncbi.nlm.nih.gov/pubmed/16682530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200602054
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