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Drosophila melanogaster auxilin regulates the internalization of Delta to control activity of the Notch signaling pathway
We have isolated mutations in the Drosophila melanogaster homologue of auxilin, a J-domain–containing protein known to cooperate with Hsc70 in the disassembly of clathrin coats from clathrin-coated vesicles in vitro. Consistent with this biochemical role, animals with reduced auxilin function exhibi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2063844/ https://ncbi.nlm.nih.gov/pubmed/16682530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200602054 |
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