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Internalization is required for proper Wingless signaling in Drosophila melanogaster
The Wnt–Wingless (Wg) pathway regulates development through precisely controlled signaling. In this study, we show that intracellular trafficking regulates Wg signaling levels. In Drosophila melanogaster cells stimulated with Wg media, dynamin or Rab5 knockdown causes reduced Super8XTOPflash activit...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2063794/ https://ncbi.nlm.nih.gov/pubmed/16606693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200510123 |
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