Lamina-associated polypeptide 2α regulates cell cycle progression and differentiation via the retinoblastoma–E2F pathway

Lamina-associated polypeptide (LAP) 2α is a nonmembrane-bound LAP2 isoform that forms complexes with nucleoplasmic A-type lamins. In this study, we show that the overexpression of LAP2α in fibroblasts reduced proliferation and delayed entry into the cell cycle from a G0 arrest. In contrast, stable d...

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Detaylı Bibliyografya
Asıl Yazarlar: Dorner, Daniela, Vlcek, Sylvia, Foeger, Nicole, Gajewski, Andreas, Makolm, Christian, Gotzmann, Josef, Hutchison, Christopher J., Foisner, Roland
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2006
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063793/
https://ncbi.nlm.nih.gov/pubmed/16606692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200511149
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