Lamina-associated polypeptide 2α regulates cell cycle progression and differentiation via the retinoblastoma–E2F pathway

Lamina-associated polypeptide (LAP) 2α is a nonmembrane-bound LAP2 isoform that forms complexes with nucleoplasmic A-type lamins. In this study, we show that the overexpression of LAP2α in fibroblasts reduced proliferation and delayed entry into the cell cycle from a G0 arrest. In contrast, stable d...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dorner, Daniela, Vlcek, Sylvia, Foeger, Nicole, Gajewski, Andreas, Makolm, Christian, Gotzmann, Josef, Hutchison, Christopher J., Foisner, Roland
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2006
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063793/
https://ncbi.nlm.nih.gov/pubmed/16606692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200511149
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak