RGMa inhibition promotes axonal growth and recovery after spinal cord injury

Repulsive guidance molecule (RGM) is a protein implicated in both axonal guidance and neural tube closure. We report RGMa as a potent inhibitor of axon regeneration in the adult central nervous system (CNS). RGMa inhibits mammalian CNS neurite outgrowth by a mechanism dependent on the activation of...

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Main Authors: Hata, Katsuhiko, Fujitani, Masashi, Yasuda, Yuichi, Doya, Hideo, Saito, Tomoko, Yamagishi, Satoru, Mueller, Bernhard K., Yamashita, Toshihide
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2006
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063787/
https://ncbi.nlm.nih.gov/pubmed/16585268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200508143
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