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RGMa inhibition promotes axonal growth and recovery after spinal cord injury
Repulsive guidance molecule (RGM) is a protein implicated in both axonal guidance and neural tube closure. We report RGMa as a potent inhibitor of axon regeneration in the adult central nervous system (CNS). RGMa inhibits mammalian CNS neurite outgrowth by a mechanism dependent on the activation of...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2063787/ https://ncbi.nlm.nih.gov/pubmed/16585268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200508143 |
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