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Motor neuron targeting of IGF-1 attenuates age-related external Ca(2+)-dependent skeletal muscle contraction in senescent mice
A population of fast muscle fibers from aging mice is dependent on external Ca(2+) to maintain tetanic force during repeated contractions. We hypothesized that age-related denervation in muscle fibers plays a role in initiating this contractile deficit, and that prevention of denervation by IGF-1 ov...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2063746/ https://ncbi.nlm.nih.gov/pubmed/17174053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2006.11.003 |
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