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Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression
Separase is a protease whose liberation from its inhibitory chaperone Securin triggers sister chromatid disjunction at anaphase onset in yeast by cleaving cohesin's kleisin subunit. We have created conditional knockout alleles of the mouse Separase and Securin genes. Deletion of both copies of...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2063729/ https://ncbi.nlm.nih.gov/pubmed/16533945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200506119 |
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