Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73

Transcriptional disturbance is implicated in the pathology of polyglutamine diseases, including Huntington's disease (HD). However, it is unknown whether transcriptional repression leads to neuronal death or what forms that death might take. We found transcriptional repression-induced atypical...

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Hauptverfasser: Hoshino, Masataka, Qi, Mei-ling, Yoshimura, Natsue, Miyashita, Tomoyuki, Tagawa, Kazuhiko, Wada, Yo-ichi, Enokido, Yasushi, Marubuchi, Shigeki, Harjes, Phoebe, Arai, Nobutaka, Oyanagi, Kiyomitsu, Blandino, Giovanni, Sudol, Marius, Rich, Tina, Kanazawa, Ichiro, Wanker, Erich E., Saitoe, Minoru, Okazawa, Hitoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2006
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063678/
https://ncbi.nlm.nih.gov/pubmed/16461361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200509132
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