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NEDD1-dependent recruitment of the γ-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly

The centrosome is the major microtubule organizing structure in somatic cells. Centrosomal microtubule nucleation depends on the protein γ-tubulin. In mammals, γ-tubulin associates with additional proteins into a large complex, the γ-tubulin ring complex (γTuRC). We characterize NEDD1, a centrosomal...

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Autors principals: Haren, Laurence, Remy, Marie-Hélène, Bazin, Ingrid, Callebaut, Isabelle, Wright, Michel, Merdes, Andreas
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063671/
https://ncbi.nlm.nih.gov/pubmed/16461362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200510028
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