Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation

Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. Components of both productive folding and ER-associated degradation (ERAD) mechanisms are known to be up-regulated by the unfolded protein response (UPR). We...

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Main Authors: Oda, Yukako, Okada, Tetsuya, Yoshida, Hiderou, Kaufman, Randal J., Nagata, Kazuhiro, Mori, Kazutoshi
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2006
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063648/
https://ncbi.nlm.nih.gov/pubmed/16449189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200507057
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