Focal adhesion size controls tension-dependent recruitment of α-smooth muscle actin to stress fibers

Expression of α-smooth muscle actin (α-SMA) renders fibroblasts highly contractile and hallmarks myofibroblast differentiation. We identify α-SMA as a mechanosensitive protein that is recruited to stress fibers under high tension. Generation of this threshold tension requires the anchoring of stress...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Goffin, Jérôme M., Pittet, Philippe, Csucs, Gabor, Lussi, Jost W., Meister, Jean-Jacques, Hinz, Boris
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2006
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063555/
https://ncbi.nlm.nih.gov/pubmed/16401722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200506179
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