Mining Predicted Essential Genes of Brugia malayi for Nematode Drug Targets

We report results from the first genome-wide application of a rational drug target selection methodology to a metazoan pathogen genome, the completed draft sequence of Brugia malayi, a parasitic nematode responsible for human lymphatic filariasis. More than 1.5 billion people worldwide are at risk o...

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Hlavní autoři: Kumar, Sanjay, Chaudhary, Kshitiz, Foster, Jeremy M., Novelli, Jacopo F., Zhang, Yinhua, Wang, Shiliang, Spiro, David, Ghedin, Elodie, Carlow, Clotilde K. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2007
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063515/
https://ncbi.nlm.nih.gov/pubmed/18000556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001189
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