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A macrolide 3-O-acyltransferase gene from the midecamycin-producing species Streptomyces mycarofaciens.

The Streptomyces mycarofaciens mdmB gene encodes a 3-O-acyltransferase that catalyzes the addition of acetyl and propionyl groups to position 3 of the lactone ring in 16-member macrolide antibiotics like midecamycin and spiramycin. A putative O-methyltransferase gene (mdmC) is immediately downstream...

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Bibliographic Details
Main Authors: Hara, O, Hutchinson, C R
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC206334/
https://ncbi.nlm.nih.gov/pubmed/1629172
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