Diuretic response to cyclophosphamide in rats bearing a matrix metalloproteinase-9-producing tumour.

When cyclophosphamide (CY) (100-120 mg kg(-1)) was administered intravenously (i.v.) to normal F-344 rats, oliguria occurred over the 5-day observation period. Conversely, in rats bearing matrix metalloproteinase-9 (MMP-9) producing 13762NF mammary adenocarcinoma (MTLn3 clone), polyuria occurred chi...

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Main Authors: Mizushima, Y., Sassa, K., Hamazaki, T., Fujishita, T., Oosaki, R., Kobayashi, M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group|1 1998
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063162/
https://ncbi.nlm.nih.gov/pubmed/9792146
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