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Genetic analysis of lung tumours of non-smoking subjects: p53 gene mutations are constantly associated with loss of heterozygosity at the FHIT locus.

Lung cancer is strictly associated with tobacco smoking. Tumours developed in non-smoking subjects account for less than 10% of all lung cancers and show peculiar histopathological features, being prevalently adenocarcinomas. A number of genetic data suggest that their biological behaviour may be di...

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Autors principals: Marchetti, A., Pellegrini, S., Sozzi, G., Bertacca, G., Gaeta, P., Buttitta, F., Carnicelli, V., Griseri, P., Chella, A., Angeletti, C. A., Pierotti, M., Bevilacqua, G.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group|1 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2062949/
https://ncbi.nlm.nih.gov/pubmed/9662254
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