CD8(+) T Cells from SIV Elite Controller Macaques Recognize Mamu-B*08-Bound Epitopes and Select for Widespread Viral Variation

BACKGROUND: It is generally accepted that CD8(+) T cell responses play an important role in control of immunodeficiency virus replication. The association of HLA-B27 and -B57 with control of viremia supports this conclusion. However, specific correlates of viral control in individuals expressing the...

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Autors principals: Loffredo, John T., Friedrich, Thomas C., León, Enrique J., Stephany, Jason J., Rodrigues, Denise S., Spencer, Sean P., Bean, Alex T., Beal, Dominic R., Burwitz, Benjamin J., Rudersdorf, Richard A., Wallace, Lyle T., Piaskowski, Shari M., May, Gemma E., Sidney, John, Gostick, Emma, Wilson, Nancy A., Price, David A., Kallas, Esper G., Piontkivska, Helen, Hughes, Austin L., Sette, Alessandro, Watkins, David I.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2062500/
https://ncbi.nlm.nih.gov/pubmed/18000532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001152
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