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Characterization of enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity.

We have begun a biochemical-genetic analysis of the synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae and found evidence for the occurrence of serine palmitoyltransferase (SPT) and 3-ketosphinganine reductase, enzymes that catalyze the initial steps of the pathway in other organ...

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Dades bibliogràfiques
Publicat a:J Bacteriol
Autors principals: Pinto, W J, Wells, G W, Lester, R L
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205896/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1556076/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.174.8.2575-2581.1992
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