Characterization of enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity.

We have begun a biochemical-genetic analysis of the synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae and found evidence for the occurrence of serine palmitoyltransferase (SPT) and 3-ketosphinganine reductase, enzymes that catalyze the initial steps of the pathway in other organ...

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Vydáno v:	J Bacteriol
Hlavní autoři:	Pinto, W J, Wells, G W, Lester, R L
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1992
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205896/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1556076/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.174.8.2575-2581.1992
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