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A substance P antagonist, RP-67,580, ameliorates a mouse meningoencephalitic response to Trypanosoma brucei brucei

Mice infected with the protozoan parasite Trypanosoma brucei brucei and treated subcuratively with the trypanocidal drug diminazene aceturate develop an acute inflammatory meningoencephalitis with associated astrocytic proliferation. This reaction is very similar to that seen in the fatal posttreatm...

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Detalhes bibliográficos
Main Authors: Kennedy, Peter G. E., Rodgers, Jean, Jennings, Francis W., Murray, Max, Leeman, Susan E., Burke, Joanne M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20588/
https://ncbi.nlm.nih.gov/pubmed/9108123
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