Mice devoid of γ-aminobutyrate type A receptor β3 subunit have epilepsy, cleft palate, and hypersensitive behavior

γ-Aminobutyric acid type A receptors (GABA(A)-Rs) mediate the bulk of rapid inhibitory synaptic transmission in the central nervous system. The β3 subunit is an essential component of the GABA(A)-R in many brain regions, especially during development, and is implicated in several pathophysiologic pr...

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Autori principali: Homanics, Gregg E., DeLorey, Timothy M., Firestone, Leonard L., Quinlan, Joseph J., Handforth, Adrian, Harrison, Neil L., Krasowski, Matthew D., Rick, Caroline E. M., Korpi, Esa R., Mäkelä, Riikka, Brilliant, Murray H., Hagiwara, Nobuko, Ferguson, Carolyn, Snyder, Kimberly, Olsen, Richard W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC20582/
https://ncbi.nlm.nih.gov/pubmed/9108119
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