Mice devoid of γ-aminobutyrate type A receptor β3 subunit have epilepsy, cleft palate, and hypersensitive behavior

γ-Aminobutyric acid type A receptors (GABA(A)-Rs) mediate the bulk of rapid inhibitory synaptic transmission in the central nervous system. The β3 subunit is an essential component of the GABA(A)-R in many brain regions, especially during development, and is implicated in several pathophysiologic pr...

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Hauptverfasser: Homanics, Gregg E., DeLorey, Timothy M., Firestone, Leonard L., Quinlan, Joseph J., Handforth, Adrian, Harrison, Neil L., Krasowski, Matthew D., Rick, Caroline E. M., Korpi, Esa R., Mäkelä, Riikka, Brilliant, Murray H., Hagiwara, Nobuko, Ferguson, Carolyn, Snyder, Kimberly, Olsen, Richard W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences of the USA 1997
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20582/
https://ncbi.nlm.nih.gov/pubmed/9108119
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