Cloning and analysis of a locus (mcr) involved in mitomycin C resistance in Streptomyces lavendulae.

Two genes (mcrA and mcrB) from Streptomyces lavendulae that together confer resistance to mitomycin C were identified. This DNA appears to comprise a polycistronic operon with a drug-inducible leaderless mRNA. The deduced amino acid sequence of mcrA shows similarity to sequences of a special class o...

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Pubblicato in:	J Bacteriol
Autori principali:	August, P. R., Flickinger, M. C., Sherman, D. H.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7517396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.14.4448-4454.1994
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