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Cloning and analysis of a locus (mcr) involved in mitomycin C resistance in Streptomyces lavendulae.

Two genes (mcrA and mcrB) from Streptomyces lavendulae that together confer resistance to mitomycin C were identified. This DNA appears to comprise a polycistronic operon with a drug-inducible leaderless mRNA. The deduced amino acid sequence of mcrA shows similarity to sequences of a special class o...

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Detalhes bibliográficos
Main Authors: August, P. R., Flickinger, M. C., Sherman, D. H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC205660/
https://ncbi.nlm.nih.gov/pubmed/7517396
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