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Techniques used in studies of epigenome dysregulation due to aberrant DNA methylation: an emphasis on fetal-based adult diseases

Epigenetic changes are heritable modifications that do not involve alterations in the primary DNA sequence. They regulate crucial cellular functions such as genome stability, X-chromosome inactivation, and gene imprinting. Epidemiological and experimental observations now suggest that such changes m...

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Detalhes bibliográficos
Main Authors: Ho, Shuk-mei, Tang, Wan-yee
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2055548/
https://ncbi.nlm.nih.gov/pubmed/17317097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2007.01.004
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