Loss of protein kinase-catalyzed phosphorylation of HPr, a phosphocarrier protein of the phosphotransferase system, by mutation of the ptsH gene confers catabolite repression resistance to several catabolic genes of Bacillus subtilis.

In gram-positive bacteria, HPr, a phosphocarrier protein of the phosphoenolpyruvate:sugar phosphotransferase system (PTS), is phosphorylated by an ATP-dependent, metabolite-activated protein kinase on seryl residue 46. In a Bacillus subtilis mutant strain in which Ser-46 of HPr was replaced with a n...

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Pubblicato in:	J Bacteriol
Autori principali:	Deutscher, J, Reizer, J, Fischer, C, Galinier, A, Saier, M H, Steinmetz, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205505/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8195089/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.11.3336-3344.1994
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