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Loss of protein kinase-catalyzed phosphorylation of HPr, a phosphocarrier protein of the phosphotransferase system, by mutation of the ptsH gene confers catabolite repression resistance to several catabolic genes of Bacillus subtilis.

In gram-positive bacteria, HPr, a phosphocarrier protein of the phosphoenolpyruvate:sugar phosphotransferase system (PTS), is phosphorylated by an ATP-dependent, metabolite-activated protein kinase on seryl residue 46. In a Bacillus subtilis mutant strain in which Ser-46 of HPr was replaced with a n...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Deutscher, J, Reizer, J, Fischer, C, Galinier, A, Saier, M H, Steinmetz, M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1994
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205505/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8195089/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.11.3336-3344.1994
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