Site-directed mutagenesis of the mecA gene from a methicillin-resistant strain of Staphylococcus aureus.

The mecA-27r gene from Staphylococcus aureus 27r encodes penicillin-binding protein 2a (PBP2a-27r), which causes this strain to be methicillin resistant. Removal or replacement of the N-terminal transmembrane domain had no effect on binding of penicillin, but removal of portions of the putative tran...

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Bibliografiske detaljer

Udgivet i:	J Bacteriol
Principais autores:	Wu, C Y, Alborn, W E, Flokowitsch, J E, Hoskins, J, Unal, S, Blaszczak, L C, Preston, D A, Skatrud, P L
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205068/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8288540/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.2.443-449.1994
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