Site-directed mutagenesis of the mecA gene from a methicillin-resistant strain of Staphylococcus aureus.

The mecA-27r gene from Staphylococcus aureus 27r encodes penicillin-binding protein 2a (PBP2a-27r), which causes this strain to be methicillin resistant. Removal or replacement of the N-terminal transmembrane domain had no effect on binding of penicillin, but removal of portions of the putative tran...

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Main Authors: Wu, C Y, Alborn, W E, Flokowitsch, J E, Hoskins, J, Unal, S, Blaszczak, L C, Preston, D A, Skatrud, P L
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC205068/
https://ncbi.nlm.nih.gov/pubmed/8288540
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