Basic helix–loop–helix protein E47-mediated p21Waf1/Cip1 gene expression regulates apoptosis of intestinal epithelial cells

Inhibition of ornithine decarboxylase by DFMO (α-difluromethylornithine) and subsequent polyamine depletion increases p21Cip1 protein, induces cell cycle arrest and confers resistance to apoptosis on intestinal epithelial cells. However, the mechanism by which polyamines regulate p21Cip1 expression...

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Hlavní autoři: Bhattacharya, Sujoy, Guo, Huazhang, Ray, Ramesh M., Johnson, Leonard R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2007
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2049013/
https://ncbi.nlm.nih.gov/pubmed/17617061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070293
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