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Basic helix–loop–helix protein E47-mediated p21Waf1/Cip1 gene expression regulates apoptosis of intestinal epithelial cells

Inhibition of ornithine decarboxylase by DFMO (α-difluromethylornithine) and subsequent polyamine depletion increases p21Cip1 protein, induces cell cycle arrest and confers resistance to apoptosis on intestinal epithelial cells. However, the mechanism by which polyamines regulate p21Cip1 expression...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Bhattacharya, Sujoy, Guo, Huazhang, Ray, Ramesh M., Johnson, Leonard R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Portland Press Ltd. 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2049013/
https://ncbi.nlm.nih.gov/pubmed/17617061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070293
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