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MOZ-TIF2 repression of nuclear receptor-mediated transcription requires multiple domains in MOZ and in the CID domain of TIF2

BACKGROUND: Fusion of the MOZ and TIF2 genes by an inv (8) (p11q13) translocation has been identified in patients with acute mixed-lineage leukemia. Characterization of the molecular structure of the MOZ-TIF2 fusion protein suggested that the fusion protein would effect on nuclear receptor signaling...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yin, Hong, Glass, Jonathan, Blanchard, Kerry L
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central|1 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048977/
https://ncbi.nlm.nih.gov/pubmed/17697320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-6-51
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