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Lack of MK2 Inhibits Myofibroblast Formation and Exacerbates Pulmonary Fibrosis

Fibroblasts play a major role in tissue repair and remodeling. Their differentiation into myofibroblasts, marked by increased expression of smooth muscle–specific α-actin (α-SMA), is believed to be important in wound healing and fibrosis. We have recently described a role for MK2 in this phenotypic...

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Hlavní autoři: Liu, Tiegang, Warburton, Rod R., Guevara, Oscar E., Hill, Nicholas S., Fanburg, Barry L., Gaestel, Matthias, Kayyali, Usamah S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048679/
https://ncbi.nlm.nih.gov/pubmed/17600313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0077OC
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