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Alteration of NF-κB activity leads to mitochondrial apoptosis after infection with pathological prion protein

Nuclear factor kappa B (NF-κB) is a key regulator of the immune response, but in almost the same manner it is involved in induction of inflammation, proliferation and regulation of apoptosis. In the central nervous system activated NF-κB plays a neuroprotective role. While in some neurodegenerative...

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Detalhes bibliográficos
Main Authors: Bourteele, Soizic, Oesterle, Katja, Weinzierl, Andreas O, Paxian, Stephan, Riemann, Marc, Schmid, Roland M, Planz, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048569/
https://ncbi.nlm.nih.gov/pubmed/17573907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2007.00950.x
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