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Alteration of NF-κB activity leads to mitochondrial apoptosis after infection with pathological prion protein

Nuclear factor kappa B (NF-κB) is a key regulator of the immune response, but in almost the same manner it is involved in induction of inflammation, proliferation and regulation of apoptosis. In the central nervous system activated NF-κB plays a neuroprotective role. While in some neurodegenerative...

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Bibliografiske detaljer
Main Authors: Bourteele, Soizic, Oesterle, Katja, Weinzierl, Andreas O, Paxian, Stephan, Riemann, Marc, Schmid, Roland M, Planz, Oliver
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048569/
https://ncbi.nlm.nih.gov/pubmed/17573907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2007.00950.x
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