Alteration of NF-κB activity leads to mitochondrial apoptosis after infection with pathological prion protein

Nuclear factor kappa B (NF-κB) is a key regulator of the immune response, but in almost the same manner it is involved in induction of inflammation, proliferation and regulation of apoptosis. In the central nervous system activated NF-κB plays a neuroprotective role. While in some neurodegenerative...

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Hlavní autoři: Bourteele, Soizic, Oesterle, Katja, Weinzierl, Andreas O, Paxian, Stephan, Riemann, Marc, Schmid, Roland M, Planz, Oliver
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2007
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048569/
https://ncbi.nlm.nih.gov/pubmed/17573907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2007.00950.x
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