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Differential effects of bupivacaine and tetracaine on capsaicin-induced currents in dorsal root ganglion neurons

Capsaicin opens the TRPV1 channel, a cation channel that depolarizes and activates nociceptive neurons. Following this initial activation, neurons become desensitized to subsequent applications of capsaicin as well as to other noxious stimuli, a phenomenon attributed primarily to the entry of Ca(2+)...

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Detalhes bibliográficos
Main Authors: Komai, Hirochika, McDowell, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2046220/
https://ncbi.nlm.nih.gov/pubmed/15854744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2005.01.004
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