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Amyloid β-peptide stimulates nitric oxide production in astrocytes through an NFκB-dependent mechanism

The major pathological features of Alzheimer’s disease (AD) include amyloid plaques composed primarily of the β-amyloid (Aβ) peptide, degenerating neurons and neurofibrillary tangles, and the presence of numerous activated astrocytes and microglia. Although extensive genetic data implicate Aβ in the...

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Detalhes bibliográficos
Main Authors: Akama, Keith T., Albanese, Chris, Pestell, Richard G., Van Eldik, Linda J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20459/
https://ncbi.nlm.nih.gov/pubmed/9576964
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