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Cholesterol suppresses cellular TGF-β responsiveness: implications in atherogenesis

Hypercholesterolemia is a major causative factor for atherosclerotic cardiovascular disease. The molecular mechanisms by which cholesterol initiates and facilitates the process of atherosclerosis are not well understood. Here, we demonstrate that cholesterol treatment suppresses or attenuates TGF-β...

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Main Authors: Chen, Chun-Lin, Liu, I-Hua, Fliesler, Steven J., Han, Xianlin, Huang, Shuan Shian, Huang, Jung San
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045688/
https://ncbi.nlm.nih.gov/pubmed/17878231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.006916
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