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Cholesterol Modulates Cellular TGF-β Responsiveness by Altering TGF-β Binding to TGF-β Receptors

Transforming growth factor-β (TGF-β) responsiveness in cultured cells can be modulated by TGF-β partitioning between lipid raft/caveolae- and clathrin-mediated endocytosis pathways. The TbR-II/TbR-I binding ratio of TGF-β on the cell surface has recently been found to be a signal that controls TGF-β...

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Bibliografske podrobnosti
izdano v:J Cell Physiol
Main Authors: CHEN, CHUN-LIN, HUANG, SHUAN SHIAN, HUANG, JUNG SAN
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108542/
https://ncbi.nlm.nih.gov/pubmed/17972267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21303
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