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Cholesterol Modulates Cellular TGF-β Responsiveness by Altering TGF-β Binding to TGF-β Receptors

Transforming growth factor-β (TGF-β) responsiveness in cultured cells can be modulated by TGF-β partitioning between lipid raft/caveolae- and clathrin-mediated endocytosis pathways. The TbR-II/TbR-I binding ratio of TGF-β on the cell surface has recently been found to be a signal that controls TGF-β...

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Publicado en:J Cell Physiol
Autores principales: CHEN, CHUN-LIN, HUANG, SHUAN SHIAN, HUANG, JUNG SAN
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108542/
https://ncbi.nlm.nih.gov/pubmed/17972267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21303
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