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OX40 signaling directly triggers the antitumor effects of NKT cells

Pathways involving the costimulatory molecule OX40 and OX40 ligand (OX40L) enhance tumor rejection. It was presumed that this effect was mediated by changes in DCs and/or T cells. In this issue of the JCI, Zaini et al. report that, in mice, intratumoral injection of DCs genetically modified to expre...

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Autor principal: Zhou, Dapeng
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045624/
https://ncbi.nlm.nih.gov/pubmed/17975660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33976
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