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Cyclodextrins Inhibit Replication of Scrapie Prion Protein in Cell Culture
Prion diseases are fatal neurodegenerative disorders that are caused by the conversion of a normal host-encoded protein, PrP(C), to an abnormal, disease-causing form, PrP(Sc). This paper reports that cyclodextrins have the ability to reduce the pathogenic isoform of the prion protein PrP(Sc) to unde...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2045541/ https://ncbi.nlm.nih.gov/pubmed/17699584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02559-06 |
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