Antiretroviral Drug Therapy Alters the Profile of Human Immunodeficiency Virus Type 1-Specific T-Cell Responses and Shifts the Immunodominant Cytotoxic T-Lymphocyte Response from Gag to Pol

Antiretroviral drug therapy and cytotoxic T lymphocytes (CTL) both exert selective pressures on human immunodeficiency virus type 1, which influence viral evolution. Compared to chronically infected, antiretroviral-untreated patients, most chronically infected, treated patients with detectable virem...

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Main Authors: Karlsson, A. C., Chapman, J. M., Heiken, B. D., Hoh, R., Kallas, E. G., Martin, J. N., Hecht, F. M., Deeks, S. G., Nixon, D. F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045537/
https://ncbi.nlm.nih.gov/pubmed/17670829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00779-07
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