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The Coronavirus Spike Protein Induces Endoplasmic Reticulum Stress and Upregulation of Intracellular Chemokine mRNA Concentrations

Murine hepatitis virus (MHV) and severe acute respiratory syndrome (SARS) coronavirus (CoV) are two of the best-studied representatives of the family Coronaviridae. During CoV infection, numerous cytokines and chemokines are induced in vitro and in vivo. Human interleukin 8 and its mouse functional...

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Main Authors: Versteeg, Gijs A., van de Nes, Paula S., Bredenbeek, Peter J., Spaan, Willy J. M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045536/
https://ncbi.nlm.nih.gov/pubmed/17670839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01033-07
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