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The Spike Protein of Murine Coronavirus Regulates Viral Genome Transport from the Cell Surface to the Endoplasmic Reticulum during Infection
We observed that the nonfusogenic mouse hepatitis virus (MHV) strain MHV-2 reached a titer of ∼2 log(10) higher than that of the fusogenic strain A59 in astrocytoma DBT cells. To determine whether the spike protein is responsible for the difference, a recombinant virus, Penn-98-1, that contains the...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology (ASM)
2009
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753108/ https://ncbi.nlm.nih.gov/pubmed/19570858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00956-09 |
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