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The Spike Protein of Murine Coronavirus Regulates Viral Genome Transport from the Cell Surface to the Endoplasmic Reticulum during Infection

We observed that the nonfusogenic mouse hepatitis virus (MHV) strain MHV-2 reached a titer of ∼2 log(10) higher than that of the fusogenic strain A59 in astrocytoma DBT cells. To determine whether the spike protein is responsible for the difference, a recombinant virus, Penn-98-1, that contains the...

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Detalhes bibliográficos
Main Authors: Zhu, Hongqing, Yu, Dongdong, Zhang, Xuming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753108/
https://ncbi.nlm.nih.gov/pubmed/19570858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00956-09
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