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Alanine Scanning of the Hepatitis C Virus Core Protein Reveals Numerous Residues Essential for Production of Infectious Virus

Hepatitis C virus (HCV) is an important human pathogen affecting an estimated 3% of the world's population. Recent advances have enabled in vitro propagation of the virus and allow assembly and egress to be investigated for the first time. As a component of the virion, the HCV core protein like...

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Autori principali: Murray, Catherine L., Jones, Christopher T., Tassello, Jodie, Rice, Charles M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045476/
https://ncbi.nlm.nih.gov/pubmed/17634240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00793-07
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