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Kaposi's Sarcoma-Associated Herpesvirus ORF57 Protein Enhances mRNA Accumulation Independently of Effects on Nuclear RNA Export

The ORF57 protein expressed by Kaposi's sarcoma-associated herpesvirus (KSHV) during lytic replication is essential for KSHV virion production. ORF57 enhances gene expression by increasing accumulation of target gene mRNAs. ORF57 interacts with the cellular export factor REF and with RNA, sugge...

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Bibliografiske detaljer
Main Authors: Nekorchuk, Michael, Han, Zhao, Hsieh, Ting-Ting, Swaminathan, Sankar
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045429/
https://ncbi.nlm.nih.gov/pubmed/17609285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00896-07
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