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Kaposi's Sarcoma-Associated Herpesvirus ORF57 Protein Enhances mRNA Accumulation Independently of Effects on Nuclear RNA Export

The ORF57 protein expressed by Kaposi's sarcoma-associated herpesvirus (KSHV) during lytic replication is essential for KSHV virion production. ORF57 enhances gene expression by increasing accumulation of target gene mRNAs. ORF57 interacts with the cellular export factor REF and with RNA, sugge...

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Detalhes bibliográficos
Main Authors: Nekorchuk, Michael, Han, Zhao, Hsieh, Ting-Ting, Swaminathan, Sankar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045429/
https://ncbi.nlm.nih.gov/pubmed/17609285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00896-07
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