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Even Attenuated Bovine Leukemia Virus Proviruses Can Be Pathogenic in Sheep

Based on a reverse genetics approach, we previously reported that bovine leukemia virus (BLV) mutants harboring deletions in the accessory R3 and G4 genes persist at very low proviral loads and are unable to induce leukemia or lymphoma in sheep, indicating that these R3 and G4 gene sequences are req...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Florins, Arnaud, Gillet, Nicolas, Boxus, Mathieu, Kerkhofs, Pierre, Kettmann, Richard, Willems, Luc
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045414/
https://ncbi.nlm.nih.gov/pubmed/17626096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01058-07
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