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Even Attenuated Bovine Leukemia Virus Proviruses Can Be Pathogenic in Sheep

Based on a reverse genetics approach, we previously reported that bovine leukemia virus (BLV) mutants harboring deletions in the accessory R3 and G4 genes persist at very low proviral loads and are unable to induce leukemia or lymphoma in sheep, indicating that these R3 and G4 gene sequences are req...

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Detalhes bibliográficos
Main Authors: Florins, Arnaud, Gillet, Nicolas, Boxus, Mathieu, Kerkhofs, Pierre, Kettmann, Richard, Willems, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045414/
https://ncbi.nlm.nih.gov/pubmed/17626096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01058-07
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