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CD40-CD40 Ligand Interactions Promote Trafficking of CD8(+) T Cells into the Brain and Protection against West Nile Virus Encephalitis
Recent studies have established a protective role for T cells during primary West Nile virus (WNV) infection. Binding of CD40 by CD40 ligand (CD40L) on activated CD4(+) T cells provides an important costimulatory signal for immunoglobulin class switching, antibody affinity maturation, and priming of...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2045405/ https://ncbi.nlm.nih.gov/pubmed/17626103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00941-07 |
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